“…studies show that the worse side effects a patient experiences, the more effective the drug. Patients apparently think, this drug is so strong it’s making me vomit and hate sex, so it must be strong enough to lift my depression. In clinical-trial patients who figure out they’re receiving the drug and not the inert pill, expectations soar. That matters because belief in the power of a medical treatment can be self-fulfilling (that’s the basis of the placebo effect).”
Perhaps I should explain the title of this post.
You’re all familiar with the philosophical riddle, “If a tree falls in a forest and no one is around to hear it, does it make a sound?” Well, an article in the February 8, 2010 issue of Newsweek magazine (“The Depressing News About Antidepressants,” by Sharon Begley) about antidepressants had me wondering; if a pill that is swallowed that is basically sugar, with no chemical component that might effect serotonin, works because we “believe” it works…does it “really” work?
“…scientists who study depression and the drugs that treat it are concluding…that antidepressants are basically expensive Tic Tacs.”
I’m a firm believer in the power of the mind. I’ve witnessed first hand how thinking can make it so. I do believe that, in some instances, there is such a thing as a self-fulfilling prophecy. BUT…
But, the chances of it working are about as good as your chances at the blackjack table in Vegas. Sure, sometimes you’ll draw an ace and a jack, and sometimes people get better because they believe they will, but not always. If just wishing could make it so, I’d have a brand new Maserati (GranCabrio convertible in Blu Oceano with a Sabbia interior) sitting in my driveway.
Here’s another question I had after reading the article: What happens to the placebo effect after people read an article like this one? Great! Now the pills that don’t really work, really don’t work because we’ve lost faith in them. Now what do we do?
The power of positive thinking has its place. In fact, it wouldn’t hurt to practice that in your daily life, pills or no pills. Accentuate the positive, as they say. But also, be realistic. But wait, how can you be realistic and hope to cure your depression with blind faith?
But then again…I’ll bet there are a number of Pharmaceutical sales reps out there who do have Maseratis in their garages because they visualized them. Because they held a picture of them in their mind and repeated a mantra over an over again while they fudged the test results and made promises to general practitioners that the pills couldn’t possibly deliver.
“If placebos can make people better, then depression can be treated without drugs that come with serious side effects, not to mention costs.”
Hey, it’s worth a try. If you wouldn’t mind, I’d like to try an experiment of my own. Here’s a photo of the car.
If you would just stare at it for a few minutes and repeat over and over, “A Maserati in Marco’s driveway,” I’ll let you know what happens. If I go out there tomorrow and there’s a blue convertible, I’ll be first in line to refill my prescription for Zoloft.
But until then, I’m remaining drug free!!!!